The numerous sanctuaries of the Macedonian cities (Dion, Thessalonike, Pella, Amphipolis, Edessa) were either scattered about the city or concentrated in its religious center. The absence of their architectural remains is due to the lack of resistant building materials (such as marble) for the construction of monuments.
In sanctuaries built of plastered limestone blocks and unbaked bricks, Zeus, Athena, Demeter, Dionysos, Artemis, Aphrodite, Asklepios, Herakles, and the Muses -- among others -- were worshipped under a variety of epithets.
In the Hellenistic period the cult of various eastern deities, such as Serapis and Isis, was also introduced. To these divinities were added under the Romans the deified emperors (at Beroia, Thasos, Philippi). The cult of autochthonous gods was often combined with that of eastern deities in shrines containing small 'oikoi' (Dion, sacred precint of Isis).